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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
5.5 DPC

8 matching records from 8 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Otx2  orthodenticle homeobox 2   (Synonyms: E130306E05Rik)
Results  Reference
1J:191079 Acampora D, Di Giovannantonio LG, Simeone A, Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition. Development. 2013 Jan 1;140(1):43-55
1J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64
1J:222398 Hoshino H, Shioi G, Aizawa S, AVE protein expression and visceral endoderm cell behavior during anterior-posterior axis formation in mouse embryos: Asymmetry in OTX2 and DKK1 expression. Dev Biol. 2015 Jun 15;402(2):175-91
1*J:35538 Mallamaci A, Di Blas E, Briata P, Boncinelli E, Corte G, OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area. Mech Dev. 1996 Aug;58(1-2):165-78
1J:258132 Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK, Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife. 2018 Feb 7;7:e32839
1J:298899 Neagu A, van Genderen E, Escudero I, Verwegen L, Kurek D, Lehmann J, Stel J, Dirks RAM, van Mierlo G, Maas A, Eleveld C, Ge Y, den Dekker AT, Brouwer RWW, van IJcken WFJ, Modic M, Drukker M, Jansen JH, Rivron NC, Baart EB, Marks H, Ten Berge D, In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states. Nat Cell Biol. 2020 May;22(5):534-545
1J:273305 Senft AD, Costello I, King HW, Mould AW, Bikoff EK, Robertson EJ, Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming. Cell Rep. 2018 Aug 21;24(8):1977-1985.e7
1J:327970 Tarazi S, Aguilera-Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, Wildschutz E, Haddad M, Oldak B, Gomez-Cesar E, Livnat N, Viukov S, Lokshtanov D, Naveh-Tassa S, Rose M, Hanna S, Raanan C, Brenner O, Kedmi M, Keren-Shaul H, Lapidot T, Maza I, Novershtern N, Hanna JH, Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs. Cell. 2022 Sep 1;185(18):3290-3306.e25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory